The administration of 5% echinacoside cream did not have an additional effect on UVB-induced mouse dorsal skin erythema, dermatitis score (p = 0.6589), and thickness (p = 0.0573) in Trpv3 KO mice, as compared with the Trpv3 KO vehicle group on day 5. Here, TRPV3 is linked to skin disorder.