Okazaki et al. (2014) used a “sepsis model” of acute oxidative stress induced in mice by i.p. injection of a high dose of LPS (150 mg/kg b.w.)to analyze the effects of i.v.-injected pegylated SOD (PEG-SOD) and catalase in combination on the redox state of tissues and blood [32]. The gene discussed is SOD1; the disease is Sepsis.