IGHE and allergic disease: Thus, meat allergy is a very complex type of allergy as it involves IgE against different types of mammalian meat, e.g., beef and pork (primary meat allergy), sometimes related to milk (mainly driven by the milk allergens Bos d 4, Bos d 5, and Bos d 8), and being α-Gal-associated with increasing incidence [11,13,21,22].