About PRB, the association was robust in normal tissues (r = 0.424, p = 0.002), significantly weakened in CIN2/3 (r = 0.282, p = 0.087), recovered in CIS (r = 0.377, p = 0.004), and completely disrupted in ICC (r = −0.002, p = 0.980). The gene discussed is RB1; the disease is in situ carcinoma.