However, they (i.e., LCE1A, LCE1B, LCE1C, LCE1E, and LCE1F) can be up-regulated in lung cancer cell lines that overexpress p53 from the adenoviral vector, and in HCT116 colon cancer cell lines exposed to UV radiation [51]. Here, TP53 is linked to malignant colon neoplasm.