PRKDC and brain cancer: We noted that the overexpression of MYT1L correlated with CXCR1 mRNA levels in 4 out of 6 brain cancer cell lines (Figure 3A,B) and the induction of CXCR1 in the normal DNA-PK HEK293 and M059K cells in response to the ectopically expressed MYT1L (Figure 3C,D), supporting the opinion that CXCR1 is a transcriptional target of MYT1L.