CXCR1 and neuroblastoma: In neuroblastoma cell lines, CXCR1 was up-regulated in SH-SY5Y, SK-N-MC, and SK-N-SH lines (Figure 3B), whereas only SH-SY5Y and SK-N-MC lines displayed a positive correlation between the MYT1L protein and CXCR1 mRNA levels.