Cytotoxicity against lung cancer cell line A549 IC50 2.67 μMInhibited NF-κB DNA binding, the activity of NF-κB, nuclear translocation, and IκBα phosphorylation. The treatment of A549 cells induced apoptosis and inhibited in vitro cell migration. May be a potential NF-κB inhibitor with the ability to induce apoptosis and suppress cell migration. The gene discussed is NFKBIA; the disease is lung cancer.