In HER2-positive breast cancers, the median level of sTILs was noted to be between 15 and 20% [22,23,28,30,31], of median iTILs, it was between 3 and 10% [22,23,30], and the prevalence of the LPBC phenotype was between 10 and 11% [20,22,32]. This evidence concerns the gene ERBB2 and breast carcinoma.