Compared with diabetic cardiomyopathy mice unfed with gut content, the expression of occludin, the cardiac function, and the number of goblet cells in diabetic cardiomyopathy mice fed by gut contents were higher, whereas TLR4/MyD88 pathway-related proteins and cardiomyocyte hypertrophy were reduced [95]. Here, OCLN is linked to diabetic cardiomyopathy.