Moreover, astrocytomas are characterized typically by co-mutations in Alpha Thalassemia/Mental Retardation Syndrome X-Linked (ATRX) and TP53 genes, while oligodendrogliomas mostly feature activating mutations in the Telomerase Reverse Transcriptase (TERT) gene promoter. The gene discussed is TERT; the disease is astrocytoma (excluding glioblastoma).