TWF1 and hepatocellular carcinoma: To further explore the role of TWF1 in HCC, we used specific TWF1 siRNAs (siTWF1 #5 and siTWF1 #6) to transiently knockdown TWF1 in TKI-resistant cells and observed a significant inhibition of proliferation and colony formation ability in all cell lines with TWF1 reduction (Figure 6B,C/Figure S6C,D).