Concordantly, a strong positive correlation between miR-218-5p and SLIT2/SLIT3 expression was observed in a cohort of 450 colon adenocarcinoma (COAD) from the Encyclopedia of RNA Interactomes (ENCORI) database, suggesting the expression of miR-218-5p is directly correlated with the expression of its SLIT2 and SLIT3 host genes (Figure 7B). The gene discussed is SLIT3; the disease is colon adenocarcinoma.