Dickinson et al. focused on the inactivation status of SLIT3 and SLIT1 genes in human cancers; SLIT3 was found to be methylated in 12 out of 29 (41%) of breast cancers, 1 out of 15 (6.7%) lung cancers, 2 out of 6 (33%) colorectal cancers, and in 2 out of 7 (29%) glioma tumor cell lines, while SLIT1 expression shows neuronal specificity [40]. This evidence concerns the gene SLIT1 and colorectal cancer.