MAPT and neurodegenerative disease: To assess the potential therapeutic benefits of H. citrina Baroni extracts for other neurodegenerative diseases, a C. elegans FTDP-17 model, expressing a mutant (V337M) Tau protein (V337M, here designated mtTau), was chronically treated with the three H. citrina Baroni extracts (Figure 2A–C) [12].