“4E-BP2 deamidation rates in the neuronal projections, consisting mainly of axons, control the occurrence and progression of neurodegenerative diseases, including Alzheimer’s and Parkinson’s, and establish a unified regulatory system between four different biochemical processes: deamidation, translational control, neurodegeneration, and oxidative stress.” The gene discussed is EIF4EBP2; the disease is Parkinsonism.