The results (Figures S1 and S2) demonstrated that D-Ser administration did not cause significant differences on the indices checked in comparison to the N315 infection groups; however, D-Ser administration (N315 + D-Ser group) did alleviate some indices to certain extents in comparison to the N315 group at some time points, including hematological indices of ALY count, BAS count, LIC count, NEU count, PLT count, and biochemical indices of ALT, AST, Crea, Urea, LDH, α-HBHD, CRP, etc. The gene discussed is CRP; the disease is infection.