Another group of molecules that have recently attracted interest in cancer therapy are immunoreceptors of T cells with the immunoglobulin domain ITIM (immunoreceptor tyrosine-based inhibitory motif), TIM-3 (T-cell immunoglobulin- and mucin domain-3-containing molecule 3), and LAG-3 (lymphocyte activation gene-3) [9]. The gene discussed is HAVCR2; the disease is cancer.