Specifically, PPARα KO led to increased expression levels of Gadd45b, Nppa, Hdc, Lcn2, Il6, Sox4, Marcksl1, Saa3, Ucn2, Met, Dusp10, Elovl7, Ngf, C3, Il11, Hmox1, Alox5, Tnfsf9, Angptl4, Plin2, H19, Csf2rb, Atf3, and Col7a1 following stroke (Figure 4). The gene discussed is PLIN2; the disease is Stroke.