Specifically, PPARα KO led to increased expression levels of Gadd45b, Nppa, Hdc, Lcn2, Il6, Sox4, Marcksl1, Saa3, Ucn2, Met, Dusp10, Elovl7, Ngf, C3, Il11, Hmox1, Alox5, Tnfsf9, Angptl4, Plin2, H19, Csf2rb, Atf3, and Col7a1 following stroke (Figure 4). This evidence concerns the gene GADD45B and stroke disorder.