MUC16 and esophageal squamous cell carcinoma: Cancer cells expose cancer antigens on their surface, such as CA125 (MUC16) (cancer antigen 125), HE4 (human epididymis protein 4), WT1 (Wilms’ tumor 1), NY-ESO-1 (New York esophageal squamous cell carcinoma 1), or mesothelin, which T lymphocytes can recognize.