The short-term effects of sun exposure include sunburn, which is primarily characterized by erythema (redness) and is mediated by the release of neuropeptides, histamine, prostaglandins, serotonin, and ROS [4,5], as well as the upregulation of various pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α), IL-1, IL-6, and IL-8 [6,7]. This evidence concerns the gene TNF and Erythema.