VDAC1 and cancer: These findings support the involvement of VDAC1 in the protective effects of resveratrol at low concentrations, including its antioxidant, anti-inflammatory, and neuroprotective properties, as well as improvements in cardio-metabolic health and anti-aging effects [14,15,16,17,18,19]; furthermore, at high concentrations, it promotes cell death and acts as an anti-cancer agent [9,10,11,12].