PLA2G7 and anaphylaxis: In humans, plasma PAF-AH activity decreased in patients with inflammatory conditions, such as active systemic lupus erythematosus, necrotizing enterocolitis [27], bronchial asthma [28], sepsis [29], and severe anaphylaxis [30], compared with healthy individuals, implying an increase in plasma PAF levels through a decrease in PAF-AH activity that may contribute to the pathogenesis of these inflammatory responses.