MAPT and supranuclear palsy, progressive, 1: MAPT mutations (MAPT c.1024G>A, p. Glu342Lys, and MAPT c.1217 G>A, p. Arg406Gln) were detected among patients with PSP-RS who developed features commonly associated with synucleinopathies, including autonomic failure and dream enactment behavior [23].