The causes of this disease include generalized weakness; metabolic diseases, such as hypocalcemia, hyperestrogenism, and consequent cloacal hypertrophy; dehydration; obesity; parasitosis; neurological dysfunction; coelomic masses; overexertion (dyspnea, constipation, retained eggs, egg laying, and bladder stones); distal genital urinary/digestive tract infections; and treatments with oxytocin and oviductal neoplasia [94]. This evidence concerns the gene OXT and Other metabolic disease.