TNF and asthma: At the same time, among patients with controlled asthma, the coefficients of determination (R2) were 0.194, 0.093 and 0.152 for TNFα, IL-6 and IL-8, showing a weak dependence (r = 0.39 and r = 0.3050 for IL-6 and IL-8) and a moderate dependence (r = 0.44) for TNFα.