Numerous studies have shown that the combined determination of glial fibrillary acidic protein (GFAP) and ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) within 12 h from head injury exhibits adequate diagnostic performance in terms of excluding intracranial abnormalities for mTBI adult patients [4,5,6,7,8,9,10,11]. This evidence concerns the gene GFAP and concussion.