TRGC1 and mycosis fungoides: Interestingly, comprehensive whole-exome sequencing showed that the majority of the MF samples presented multiple TCRγ, TCRα, and TCRβ ‘clono-types’, suggesting that the initial malignant transformation may occur before TCRβ or TCRα rearrangements at the level of T-lymphocyte progenitor rather than in mature memory T-cells.