Results: The risk-prediction model for the HTN patients concomitant with NAFLD included oral antidiabetic drugs (OADs) (OR = 2.553, 95% CI: 1.368–4.763), antihypertensives (AHs) (OR = 7.303, 95% CI: 4.168–12.794), body mass index (BMI) (OR = 1.145, 95% CI: 1.084–1.209), blood urea nitrogen (BUN) (OR = 0.924, 95% CI: 0.860–0.992), triglycerides (TGs) (OR = 1.474, 95% CI: 1.201–1.809), aspartate aminotransferase (AST) (OR = 1.061, 95% CI: 1.018–1.105), and AST/ALT ratio (AAR) (OR = 0.249, 95% CI: 0.121–0.514) as significant predictors. This evidence concerns the gene GPT and hypertensive disorder.