The results showed that SLS positivity in the TP was associated with decreased OS (p < 0.001, Figure 4B) and reduced DFS (p = 0.001, Figure 4D) only for those in the T3–T4 subgroup, suggesting that a TP-specific SLS pattern for LC3A staining may be a useful prognostic biomarker for rectal cancer patients with advanced disease. The gene discussed is MAP1LC3A; the disease is rectal cancer.