Trials are underway for CAR-T cells expressing CXCR5 (NCT04153799, NCT05060796), CXCR2 (NCT05353530, NCT01740557), and CCR4 (NCT03602157) in various cancers [470] (https://clinicaltrials.gov, last accessed 31 March 2025). The gene discussed is CXCR5; the disease is cancer.