Common subtypes included in nccRCC are papillary RCC (10–15% of all RCCs), chromophobe RCC (5–10%), and RCC not further classified (NOS) (previously referred to as unclassified RCC) (5%), while less common subtypes include collecting duct carcinoma (2%) and SMARCB1-deficient renal medullary carcinoma (<1%). The gene discussed is SMARCB1; the disease is renal cell carcinoma.