Figure 6 presents the survival analysis comparing the two SKCM patient groups depending on HDAC4 expression, as previously illustrated in Figure 4 and Figure 5. The difference in patient numbers between Figure 6 compared to Figure 4 and Figure 5 was due to the lack of survival data for certain patients in the cBioPortal database. The analysis revealed that patients with low HDAC4 expression had better survival outcomes (Figure 6A,B). To enhance the generalizability of our results, Figure S5 illustrated the OS among melanoma patients grouped by high, intermediate, and low HDAC4 expression. The gene discussed is HDAC4; the disease is melanoma.