Likewise, NETs from other GI sites have their own attributes, e.g., the stomach has three distinct subtypes of NETs [39], duodenal NETs have a strong association with familial syndromes and/or gastrin/somatostatin secretion [40,41], and colonic and rectal NETs tend to be managed quite differently [42]. This evidence concerns the gene GAST and rectum neuroendocrine neoplasm.