TPI1 and Gastric Metaplasia: A similar observation was reported in gastric metaplasia induced by Helicobacter, where MDSCs exhibited high expression of genes such as Hexokinase (Hk), Triose Phosphate Isomerase (Tpi), Lactate Dehydrogenase (Ldh) and Glucose Transporter (Glut), all of which are involved in energy metabolism [62] which may also supply sufficient energy to support the immunosuppressive functions of MDSCs [63].