Thus, Guo et al. reported the development of IL-15-secreting CD70 CAR-NK cells derived from CB mononuclear cells, exhibiting a pronounced in vitro and in vivo target-dependent cytotoxicity; repetitive administrations of CD70 CAR-NK cells resulted in durable remissions in mouse models of xenotransplanted CD19− B-cell lymphomas [66]. The gene discussed is CD70; the disease is B-cell non-Hodgkin lymphoma.