YAP1 knockout resulted in the decreased proliferation of H69AR and SBC5 [70] and inhibited the growth of the H841 and SW1271 SCLC cell lines [71], which may imply that ANXA1 silencing caused increased proliferation in H1048 indirectly due to a surge in YAP1 expression. This evidence concerns the gene ANXA1 and small cell lung carcinoma.