This review aimed to synthesize current evidence on advanced technologies in robot-assisted PCa surgery, with a particular focus on the applicability of sentinel node biopsy (SNB), PSMA-RGS, and other types of fluorescence guidance for the intraoperative detection of LNMs, as well as the use of AR for avoiding PSMs during NSS, highlighting their pivotal role in driving the field toward a more precise, effective, and patient-centered surgical approach. Here, FOLH1 is linked to posterior cortical atrophy.