To evaluate the protein expression of FTO and ALKBH5 proteins in our RCC cohort relative to control samples, we performed IHC on FTO and ALKBH5 on ccRCC (n = 39), chRCC (n = 7), pRCC (n = 8), and control (n = 11) kidney FFPE samples (Figure 2a). Here, FTO is linked to nonpapillary renal cell carcinoma.