Regarding this study’s findings, human AML blasts express Cfh, Ccr3, Thbs1, Itgb3, Anp32b and Stat4, with higher expression of all being separately associated with poor prognosis (Tsao et al. 2012; –Wang et al. 2021), and expression ofCcr3in AML blasts is thought to drive chemokine induced proliferation (Wenk et al. 2018). This evidence concerns the gene ITGB3 and acute myeloid leukemia.