IL18 and skin basal cell carcinoma: The results revealed that both AMVCs and hiPSC-CMs experienced more severe cell injury in the presence of BCCs, as evidenced by a more pronounced decrease in cell viability, LDH release and IL-18 in response to DOX treatment (Fig. 1b–e, f–i), suggesting the possibility that BCC–cardiomyocyte communication aggravated DOXIC.