Similar results were obtained when OGT was knocked down with OGT-targeted siRNA (Fig. 3B) and when the co-immunoprecipitation experiments were performed in MCF7 (Fig. S4A, B) or A549 cells (Fig. S4C, D), demonstrating that cellular O-GlcNAcylation status influences interactions between DBHS proteins in various types of cancer cells. This evidence concerns the gene OGT and cancer.