In a study65on syndromic obesity, which includes obesity alongside intellectual disability and developmental delay, WES trios on 20 patients revealed pathogenic or likely pathogenic variants in 6 cases, involving genes such asMED13L,AHDC1,EHMT1,MYT1L,GRIA3, andSETD1A, while 2 patients had inherited variants of uncertain significance. The gene discussed is GRIA3; the disease is Global developmental delay.