FXN and nervous system disorder: Experimental assessments employing specialized bioinformatics protocols tailored for genome sequencing and focusing on short tandem repeat (STR) expansions have been conducted and achieved remarkable accuracy in terms of identifying neurological disorders caused by STR expansions in several patients.80These include STRs located in noncoding regions, such as the 5′ untranslated region (that is,C9orf72,FMR1, andPPP2R2B), 3′ untranslated region (that is,DMPK), and intron 1 (that is,FXN).