NFKB1 and amyotrophic lateral sclerosis: Furthermore, propionate decreased the expression of genes involved in neurologic disease and inflammatory pathways, including amyotrophic lateral sclerosis, Parkinson disease, fatty acid oxidation, NF-κB signaling, T cell factor–dependent signaling in response to WNT, class I MHC antigen processing and presentation, and the adaptive immune system (Figure 5I).