Based on the positive association between CNS-infiltrating CXCR3+ B cells and EBV viral load in people with MS (64) and our prior identification of EBV-induced CXCR3 expression (34, 48), we next evaluated expression of EBV-induced gene expression signatures within the integrated B cell scRNA-Seq data (Supplemental Table 4, Figure 2, and Supplemental Figures 5–9). The gene discussed is CXCR3; the disease is myeloid sarcoma.