EPHX2 and Alzheimer disease: Of the 23 significantly altered oxylipin in PL by AD genotype and/or TRAP exposure, 7 (30%) are proresolving or serve as precursors to proresolving mediators [5-HETE, 15-HETE, 12-oxo-ETE, 15-oxo-ETE, 8(9)-EpETrE, 15-HEPE, 17-HDoHE], 8 are proinflammatory, 6 are diols of sEH epoxide metabolism, and 2 are prostanoids.