Second, we explored whether changes in esterified oxylipins are linked to aspects of AD pathogenesis including PET imaging of translocator protein (TSPO), synaptic vesicle glycoprotein 2A (SV2A), and glucose uptake, as markers of neuroinflammation (54), synaptic loss (51), and glucose metabolism (55), respectively. The gene discussed is SV2A; the disease is Alzheimer disease.