FOXQ1 and Sepsis: The first cell population (named C5) is characterized by the expression of marker mRNAs such as Cldn16, Foxq1, and Kcnj10, while the second cell population (named C6) expresses markers such as Cldn10b and Ptger3 but notably lacks Kcnj10. The Foxq1 gene encodes the Forkhead Box Q1 transcription factor, which is involved in epithelial-to-mesenchymal transition, cell proliferation, tumor development [20, 22], and was suggested to improve renal outcomes following sepsis-induced acute kidney injury [45].