ERBB2 and breast neoplasm: The datasets in this research are publicly available at following resource: (i) 23 10× Visium Kidney samples from CKD, AKI, and Healthy (https://atlas.kpmp.org/repository/), (ii) LIBD human dorsolateral prefrontal cortex, dorsolateral prefrontal cortex 10× Visium data (http://research.libd.org/spatialLIBD/) (iii) Human breast cancer 10× Visium data (https://support.10xgenomics.com/spatial-gene-expression/datasets) (4) HER2-positive breast tumor ST data (https://zenodo.org/records/3957257).