Analysis of GBM data from The Cancer Genome Atlas (TCGA) GBM revealed that FGFR2 is frequently deleted, and several FGFR2 fusion proteins (e.g., CXCL17–FGFR2 and SIPA1L3–FGFR2) have been identified. The gene discussed is SIPA1L3; the disease is glioblastoma.