The fact that a high expression of Magmas coincides with a low expression of 4-HNE in high-grade tumours and that a high expression of 4-HNE is consistent with a low expression of Magmas in benign OC tumours, indicates that Magmas expression essentially is critical to sustaining the redox balance in ovarian tumours, as reported previously in the yeast model [35]. This evidence concerns the gene PAM16 and ovarian neoplasm.