The expression of Magmas was also shown to induce a protective role against the apoptotic stimulus of the protein kinase C (PKC) inhibitor staurosporine in the murine ACTH-secreting pituitary adenoma cell line and the rat pituitary adenoma cell line-secreting growth hormone/prolactin (GH/PRL) [36]. This evidence concerns the gene POMC and pituitary gland adenoma.