Furthermore, in rotenone-induced rat models of Parkinson’s disease, Nar has been shown to inhibit NF-κB activation, suppress neuroinflammatory mediator expression, and exert neuroprotection through modulation of slc38a2 gene expression, GABAergic synaptic transmission, and cAMP signaling pathways [25]. The gene discussed is CPSF4; the disease is Parkinson disease.