Thereafter, uPAR expression in AML blasts was reported to be heterogenous but dependent on the FAB subtype, the highest expression being in the M4-M5 groups; furthermore, regardless of the FAB subtype, high uPAR levels correlated with a more aggressive phenotype of AML cells and with a worse prognosis [33,34]. The gene discussed is PLAUR; the disease is acute myeloid leukemia.