PLAUR and acute myeloid leukemia: To elucidate whether uPAR expression in AML cell lines could be regulated by endogenously expressed selected miRs, LNAs specific for selected let-7 miRNAs or a control LNA were transfected in KG1 cells, which express higher levels of let-7 miRNAs with respect to U937 cells, as shown in Figure 3.